NKG-HM22DF | 价格

NKG-HM22DF-100μg / 询价

NKG-HM22DF-500μg / 询价

NKG-HM22DF-500μgx2 / 询价

FITC-Labeled Human NKG2D/CD314 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant FITC-Labeled Human NKG2D/CD314 Protein is expressed from HEK293 with hFc tag and Flag tag at the N-Terminus.
It contains Phe78-Val216 [Accession | P26718].

分子量大小(Molecular Weight)

The protein has a predicted MW of 43.4 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.

波长(Wavelength)

Excitation Wavelength: 490 nm

Emission Wavelength: 520 nm

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Supplied as 0.22μm filtered solution in PBS (pH 7.4).

存储(Storage)

Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

FITC-Labeled Human NKG2D on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of FITC-Labeled Human NKG2D is greater than 95% as determined by SEC-HPLC.

背景(Background)

NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma δ T cells, NK cells and NKT cells.

分子别名(Synonyms)

CD314; D12S2489E; KLR; NKG2-D; NKG2D

文献(References)

(1)Spear P , Barber A , Rynda-Apple A , et al. NKG2D CAR T-cell therapy inhibits the growth of NKG2D ligand heterogeneous tumors[J]. Immunology and Cell Biology, 2013, 91(6):435-440.